EFFICACY OF NURSE DRIVEN INTERVENTIONAL PACKAGE ON QUALITY OF LIFE AND BIOCHEMICAL MARKERS AMONG PATIENT WITH CKD”-A PILOT RANDOMIZED CONTROLLED STUDY

Authors

  • N. Rajalakshmi .
  • Dr. M. Kavitha
  • Dr. J. Anitha
  • Dr. G. Dhanalakshmi

DOI:

https://doi.org/10.52152/801126

Keywords:

Chronic Kidney Disease; holistic Intervention; Quality of Life; Biochemical Parameters; Randomized Trial.

Abstract

Objectives: Chronic kidney disease (CKD) negatively affects quality of life (QoL) and biochemical stability. This pilot randomized controlled trial evaluated the effectiveness of a nurse-led intervention (nutrition counseling, chair-based exercises, mindfulness) on QoL and biochemical parameters among CKD patients.

Methods: A pretest–posttest randomized controlled design was conducted in a tertiary nephrology unit. Twenty participants were randomized equally to intervention (n=10) or control (n=10). The intervention lasted 4 weeks. Outcomes included QoL (KDQOL-36) and biochemical parameters (serum creatinine, hemoglobin, GFR). Statistical analyses included paired t-tests and effect sizes. Ethical approval and trial registration were obtained.

Results: The intervention group showed significant improvement in QoL (t(4)=8.92, p<0.001, Cohen’s d=1.94). Biochemical trends were favorable, with reduced creatinine and improved GFR, though not statistically significant.

Conclusions: A nurse-led holistic package improved QoL and suggested stabilization of biochemical parameters. This intervention is feasible and warrants testing in larger RCTs.

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Published

2025-08-25

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How to Cite

EFFICACY OF NURSE DRIVEN INTERVENTIONAL PACKAGE ON QUALITY OF LIFE AND BIOCHEMICAL MARKERS AMONG PATIENT WITH CKD”-A PILOT RANDOMIZED CONTROLLED STUDY. (2025). Lex Localis - Journal of Local Self-Government, 23(S4), 3618-3631. https://doi.org/10.52152/801126